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Pharmaceutical Grade PVP USP 42

  • Product Name: Pharmaceutical Grade PVP USP 42
  • CasNo: 9003-39-8
  • Purity: >95%
  • Appearance: White powder
  • 25kg/drum

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CasNo: 9003-39-8

Molecular Formula: (C6H9NO)n

Appearance: White powder

Packing: 25kg/drum

Purity: >95%

Product Name:Polyvinylpyrrolidone

Chemical Description:Homopolymer of 1-Vinly-2-Pyrrolidone,Polyvinylpyrrolidone

INCI/CTFA:PVP

CAS NO.:9003-39-8

Formula structure:

Product Properties:

Technical grade PVP(PVP K Series) products are existing as powder and water solution form,and being supplied in a wide molecular weight range,easily dissolve in water,alcohol and other organic solvents.They are highly hygroscopicity,excellent film-forming capacity,adhesiveness and chemical stability,none toxicity.

 

Specifications:

Product

Povidone K15

Povidone K17

Povidone K25

Povidone K30

Povidone K60

Povidone K90

Appearance

White or yellowish-white,hygroscopic powder or flakes

Solubility

Freely soluble in water,in ethano(96%) and in methanol,very slightly soluble in acetone.

Appearance of Solution

Clearly and not moren intensely coloured than reference solution B6,BY6 or R6

Identifications

Meet ID Tests

pH Value(5% in aqueous solution)

3.0-5.0

3.0-5.0

3.0-5.0

3.0-5.0

4.0-7.0

4.0-7.0

Viscosity(Expressed as K Value)

12.75-17.25

15.3-18.36

22.5-27.0

27.0-32.4

54.0-64.8

81.0-97.2

Adehydes(Expressed as Acetaldehyde)

500 ppm max.

500 ppm max. 500 ppm max. 500 ppm max. 500 ppm max. 500 ppm max.

Peroxides(Expressed as H2O2)

400ppm max.

400 ppm max 400 ppm max 400 ppm max 400 ppm max 400 ppm max

Formic Acid

0.5% max.

0.5% max. 0.5% max. 0.5% max. 0.5% max. 0.5% max.

Hydrazine

1ppm max.

1ppm max. 1ppm max. 1ppm max. 1ppm max. 1ppm max.

N-Vinylpyrrolidone(Impurity A)

USP27

1000 ppm max.

1000 ppm max. 1000 ppm max. 1000 ppm max. 1000 ppm max. 1000 ppm max.

Current USP/EP/BP

10 ppm max.

10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max.

2-Pyrrolidone(Impurity B)

3.0% max.

3.0% max. 3.0% max. 3.0% max. 3.0% max. 3.0% max.

Heavy Metals(as Pb)

10 ppm max.

10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max. 10 ppm max.

Water

5.0% max.

5.0% max.

5.0% max.

5.0% max.

5.0% max.

5.0% max.

Sulphated Ash

0.1% max.

0.1% max.

0.1% max.

0.1% max.

0.1% max.

0.1% max.

Nitrogen Content

11.5-12.8%

11.5-12.8%

11.5-12.8%

11.5-12.8%

11.5-12.8%

11.5-12.8%

 

 

Applications:

Povidone is one of the most important excipient in the worldwide for pharmaceutical industry,

whatever for human health care products and animal health care products.It’s more and more

used as:

1)Binder for tables,capsule,

2)Sugar coatings and films,

3)Thickening agent,

4)Solubility Improver for poorly soluble drugs,

5)Bioavailability Enhancer for drug’s active ingredients,

6)Pore-forming for membrane products.

example:PVP K30 used as adhesive in medicine products,PVP-K17 for Injection purpose

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