PVP K17 (Good Solubilizing Agent)

  • CasNo:9003-39-8
  • Molecular Formula:(C6H9NO)n
  • Purity:
  • Molecular Weight:
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Product Details

CAS No.: 9003-39-8

Molecular formula:(C6H9NO)n

Molecular Weight:8000-12000

Apperance:A white to creamy white powder;

• Readily soluble in water and a variety of organic solvent;

• Pharma /EP7 / USP27/28/30/32/34/36/38 grade.

 Formula structure:

Specification(CP/BP/USP/EP)

PVPK17(Just for reference,please email us for latest COA:pvp01@shdxpvp.com)

 

TEST    ITEMS

SPECIFICATIONS

TEST    VALUE

Appearance

White powder

Conforms

Identification

conforms

Conforms

K Value

15-19

17.26

Monomer                                                      ppm

≤ 10

< 10

Moisture                                                        %

≤ 5.0

3.1

Sulfate ash                                                    %

≤ 0.1

0.051

PH value

3-7

3.55

Nitrogen                                                        %

11.5-12.8

11.96

Aldehyde (as acetaldehyde)                        %

≤ 0.05

< 0.05

Heavy metal (as lead)                                  ppm

≤ 10

< 10

Hydrazine                                                    ppm

≤ 1.0

< 1.0

 

Warm Note:

K Value(15-19)we can control the K Value to make the molecular weight to fit your project.

 

 

Packing and Storage

 

1 carboard drum 25kgs
Q'ty/20'FCL: 9MT
Q'ty/40FCL: 18MT

 

Please stored in dry place in room temperature.

 

Injectables for human and veterinary administration

When drugs are be administered by parenteral route, solubilization plays a more important role than in oral administration, as with the latter, a soild dosage form is equally acceptable. Therefore the pyrogen-free types,PVP(Povidone) K17 are recommended for parenterals. The molecular weight of this product is low enough enough(mw 9000) to allow repaid renal elimination without storage.

In some countries in Europe, like Germany and Austria,only such low-molecular polyvidone types with a K-value of up to 18 are approved for injection.

 

PVP(Povidone) K17 is nowadays widely used in antibiotic and sulfonamide formulations. Table 1 shows, how the solubilization of rifampicin depends directly on the povidone concentration.

Povidone K17 Good Solubilizing Agent

Table 2 shows the composition of a commercially available oxytetracycline preparation for injection, that containsPVP(Povidone) K17 as a solubilizing agent.

 

Table 2: Composition of a commercially available oxytetracycline ampoule

pvp k17 formulation

A positive side-effect of the use of PVP(Povidone) K17 is a reduction in the local toxicity of oxytetracycline.(from Volker Buhler-- polyvinylpyrrolidone for the pharmaceutical industry)

 

Certification

Povidone K17 Good Solubilizing Agent

Factory&QC

Povidone K17 Good Solubilizing Agent

 

Service

 

Any requirement or Questions or GOOD PRICE,

please feel free to contact us!+8618601708233

 

 

Please put our < PVP-K17 Molecular 8000 for Haemodes >into your test.

 

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